Cissus quadrangularis (Asthisamhari) is a succulent plant of family Vitaceae commonly found throughout the hotter parts of India. Cissus Quadrangularis influences early regeneration and quick mineralization of bone fracture healing process which gives it a traditional name as “bone setter” or “hadjod”. BestSource. Nutrition’s Cissus Quadrangularis Extract is standardized to 5% Ketosterone. Extraction is done by unique technology. This high quality extract from the plant is manufactured in premium facility using state of the art technology and closely controlled process.

The proliferation rate and biological activity of the osteoblasts controls the rate of bone formation, and accelerated osteoblast growth is the key factor for efficient bone repair. The active constituents of Cssus Quadrangularis may stimulate the proliferation and differentiation of MSCs and promote new bone formation through the Wnt–LRP5–ß-catenin signaling pathway for pre-osteoblast formation, as per the studies. Thus, Cissus Quadrangularis has shown to be very effective in improving bone health: ·

• By increasing the proliferation of Mesenchymal stem cells which are responsible for bone-forming osteoblasts
• By reducing the pain and swelling that is associated with bone, tendon, and ligament damage.

Cissus Quadrangularisis often suggested being of help in joint and bone health in regards to athletic adults and menopausal women. Cissus may reduce joint pain and increase mobility in athletes with exercise induced joint injuries. It can be effectively used to treat various bone disorders ( bone defects secondary to trauma, fracture) and can also be used as a preventive measure for disorders that lead to decreased bone mineral density ( osteoporosis, osteomyelitis, etc).

For adults, take one (1) – (2) veg capsule daily. Swallow the Cissus Quadrangularis Extract Veg Capsule whole. Do not puncture or open the Veg Capsule.

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Seek emergency medical attention.

Side effects: Cissus Quadrangularis Extract is likely safe but sometimes causes headache, intestinal gas, dry mouth, diarrhea, and insomnia. Drug Interactions: Cissus Quadrangularis may might lower blood sugar levels. Caution is advised in people with diabetes or low blood sugar. Risks: People who are pregnant, nursing, have diabetes should check with their health care provider before taking Cissus Quadrangularis Extract supplement. Stop using product at least 2 weeks before a scheduled surgery. Caution:If you are allergic or hypersensitive to Cissus Quadrangualris then avoid or use Cissus Quadrangularis Extract supplements cautiously.

Cissus Quadrangularis may have muscle relaxing properties after 30 minutes, suggesting it may not be a good preworkout supplement. Not intended for use by persons under the age of 18 yrs.

Store at room temperature away from sunlight & moisture. Do not freeze supplement. Safely throw away Veg Capsule that is out of date or no longer needed. Keep out of the reach of children.

1. Grasp the bottle tightly in two hands.
2. Press down on the lid while simultaneously turning it in the direction of arrow.
3. Remove the cap.
4. After removing Veg Capsule, replace the cap in same manner